Henry Sabin (1829-1918)

Florence R. Sabin, 1915

Op-molb130082 1816..1829

The Piwi-interacting RNA (piRNA) pathway defends animal genomes against the harmful consequences of transposable element (TE) infection by imposing small-RNA-mediated silencing. Because silencing is targeted by TE-derived piRNAs, piRNA production is posited to be central to the evolution of genome defense. We harnessed genomic data sets from Drosophila melanogaster, including genome-wide measur...

Op-brai130113 1816..1829

After stroke, penumbral salvage determines clinical recovery. However, the rescued penumbra may be affected by selective neuronal loss, as documented both histopathologically in animals and using the validated in vivo positron emission tomography marker C-flumazenil in humans. However, whether the non-infarcted penumbra is capable of neuronal activation, and how selective neuronal loss may inte...

Florence Rena Sabin (1871-1953)

Florence Rena Sabin [5] had successful careers as both a researcher and public health reformer. When Johns Hopkins University [6] Medical School opened, accepting women and men on the same basis, Sabin was one of the first to enter. After the successful completion of her MD degree, Sabin went on to become the first female faculty member and later full-time professor at Johns Hopkins. From 1924?...

A multivariate Powell-Sabin interpolant

We consider the problem of constructing a C1 piecewise quadratic interpolant, Q, to positional and gradient data defined at the vertices of a tessellation of n-simplices in IR. The key to the interpolation scheme is to appropriately subdivide each simplex to ensure that certain necessary geometric constraints are satisfied by the subdivision points. We establish these constraints using the Bern...